Academic Literature

Prevalence of Off-Label Use and Spending Among Patent-Protected Chemotherapies

The prevalence of off-label anticancer drug use is not well characterized.

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Originally published on 02/19/2013 in The Journal of Clinical Oncology

The extent of off-label use is a policy concern because the clinical benefits of such use to patients may not outweigh costs or adverse health outcomes.

In this study, Dr. Bach and coauthors find that patent-protected chemotherapies are used approximately 30% of the time for for off-label indications.

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